ISSN: 2960-1959
Publisher
Review Articles

Breastfeeding Impact on Cancer in Women: A Systematic Review

Aland S. Abdullah
College of Medicine, University of Sulaimani, Madam Mitterrand Street, Sulaymaniyah, Kurdistan, Iraq
Halkawt O. Ali
Scientific Affairs Department, Smart Health Tower, Madam Mitterrand Street, Sulaymaniyah, Kurdistan, Iraq
Huda M. Muhammad
College of Medicine, University of Sulaimani, Madam Mitterrand Street, Sulaymaniyah, Kurdistan, Iraq
Lana RA. Pshtiwan
Scientific Affairs Department, Smart Health Tower, Madam Mitterrand Street, Sulaymaniyah, Kurdistan, Iraq
Rebaz M. Ali
Hiwa Cancer Hospital, Sulaymaniyah, Kurdistan, Iraq
Nahida Hama Ameen Ahmed
Sulaimani Maternity Teaching Hospital, Sulaymaniyah, Kurdistan, Iraq
Snur Othman
Sulaimani Maternity Teaching Hospital, Sulaymaniyah, Kurdistan, Iraq
Karzan M. Hasan
Scientific Affairs Department, Smart Health Tower, Madam Mitterrand Street, Sulaymaniyah, Kurdistan, Iraq
Ari M. Abdullah
Sulaimani Teaching Hospital, Sulaymaniyah, Kurdistan, Iraq
Abdulwahid M. Salih
College of Medicine, University of Sulaimani, Madam Mitterrand Street, Sulaymaniyah, Kurdistan, Iraq
Fahmi H. Kakamad
College of Medicine, University of Sulaimani, Madam Mitterrand Street, Sulaymaniyah, Kurdistan, Iraq
Berun A. Abdalla
Department of Biology, College of Education, University of Sulaimani, Madam Mitterrand Street, Sulaymaniyah, Kurdistan, Iraq
Abstract
341
Downloads
170
Published: March 8, 2024
PDF
PDF

Abstract

Introduction

Many studies have emphasized the impact of breastfeeding on the health of both the mother and the infant, especially its impact on the different types of cancers that can develop in the mother. Due to the ongoing conflict regarding whether or not breastfeeding reduces, increases, or has no impact on the risk of cancer, this systematic review was conducted to settle this conflict and shed light on the issue.

Methods

The CINAHL, PubMed/MEDLINE, Cochrane Library, Web of Science, and EMBASE databases were thoroughly searched to identify any studies published in the English Language up to November 25th, 2023.

Results

Out of the initial 170 papers the systematic search brought, 16 of them met all the criteria and were left to be included in the study. A sum of 29,100 patients were included in the study with 19,905 of them having breastfed. A total of 14,817 patients were developing different types of cancer and within them, breast cancer was the most frequent. Furthermore, there seemed to be a majority association between breastfeeding and cancer in the mother as most of the studies concluded that breastfeeding is observed to decrease the risk.

Conclusion

The majority of studies support the hypothesis that breastfeeding and breastfeeding duration both lower the risk of cancer, especially breast cancer, developed in the mother.

References

  1. National Institutes of Health. About Breastfeeding and Breast Milk [Internet]. http://www.nichd.nih.gov/. 2017. Available from: https://www.nichd.nih.gov/health/topics/breastfeeding/conditioninfo
  2. World Health Organization. The physiological basis of breastfeeding. Nih.gov. World Health Organization; 2009. Available from: https://www.ncbi.nlm.nih.gov/books/NBK148970/
  3. Kim SY, Yi DY. Components of human breast milk: from macronutrient to microbiome and microRNA. Clinical and Experimental Pediatrics. 2020;63(8):301–9. doi:10.3345/cep.2020.00059
  4. Camacho-Morales A, Caba M, García-Juárez M, Caba-Flores MD, Viveros-Contreras R, Martínez-Valenzuela C. Breastfeeding Contributes to Physiological Immune Programming in the Newborn. Frontiers in pediatrics. 2021;9:744104. doi:10.3389/fped.2021.744104
  5. North K, Gao M, Allen G, Lee AC. Breastfeeding in a Global Context: Epidemiology, Impact, and Future Directions. Clinical Therapeutics. 2021;44(2). doi:10.1016/j.clinthera.2021.11.017
  6. Johnston M, Landers S, Noble L, Szucs K, Viehmann L. Breastfeeding and the use of human milk. Pediatrics. 2012;129(3):e827-41. doi:10.1542/peds.2011-3552
  7. Godfrey JR, Lawrence RA. Toward optimal health: the maternal benefits of breastfeeding. Journal of women's health. 2010;19(9):1597-602. doi:10.1089/jwh.2010.2290
  8. Dieterich CM, Felice JP, O’Sullivan E, Rasmussen KM. Breastfeeding and Health Outcomes for the Mother-Infant Dyad. Pediatric Clinics of North America. 2013;60(1):31–48. doi:10.1016/j.pcl.2012.09.010
  9. Collaborative Group on Hormonal Factors in Breast Cancer. Breast cancer and breastfeeding: collaborative reanalysis of individual data from 47 epidemiological studies in 30 countries, including 50 302 women with breast cancer and 96 973 women without the disease. The Lancet. 2002;360(9328):187–95. doi:10.1016/S0140-6736(02)09454-0
  10. Gustbée E, Anesten C, Markkula A, Simonsson M, Rose C, Ingvar C, et al. Excessive milk production during breast-feeding prior to breast cancer diagnosis is associated with increased risk for early events. SpringerPlus. 2013;2(1). doi:10.1186/2193-1801-2-298
  11. Jernström H, Lubinski J, Lynch HT, Ghadirian P, Neuhausen S, Isaacs C, et al. Breast-feeding and the Risk of Breast Cancer in BRCA1 and BRCA2 Mutation Carriers. JNCI: Journal of the National Cancer Institute. 2004;96(14):1094–8. doi:10.1093/jnci/djh211
  12. Andrieu N, Goldgar DE, Easton DF, Rookus M, Brohet R, Antoniou AC, et al. Pregnancies, Breast-Feeding, and Breast Cancer Risk in the International BRCA1/2 Carrier Cohort Study (IBCCS). JNCI: Journal of the National Cancer Institute. 2006;98(8):535–44. doi:10.1093/jnci/djj132
  13. Redondo CM, Gago-Domínguez M, Ponte SM, Castelo ME, Jiang X, García AA, et al. Breast Feeding, Parity and Breast Cancer Subtypes in a Spanish Cohort. Toland AE, editor. PLoS ONE. 2012;7(7):e40543. doi:10.1371/journal.pone.0040543
  14. Anderson JD. Breast feeding and breast cancer. South African Medical Journal. 1975;49(13):479-82. doi:N/A
  15. Abou‐Daoud KT. Cancer of the breast and breast‐feeding: Study of 279 porous women and matched controls. Cancer. 1971;28(3):781-4. doi:10.1002/1097-0142(197109)28:3%3C781::AID-CNCR2820280337%3E3.0.CO;2-B
  16. Mengesha H. Association of Non Breast Feeding and Breast Cancer among Patients on Chemotherapy and Radiotherapy at Tikur Anbessa Specialized Hospital: A Case-Control Study(Doctoral dissertation, Addis Ababa University). doi:N/A
  17. Sangaramoorthy M, Hines LM, Torres-Mejía G, Phipps AI, Baumgartner KB, Wu AH, et al. A Pooled Analysis of Breastfeeding and Breast Cancer Risk by Hormone Receptor Status in Parous Hispanic Women. Epidemiology. 2019;30(3):449–57. doi:10.1097%2FEDE.0000000000000981
  18. Afzal S, Farooqui AA, Rizwan H, Akram A, Bajwa SA, Ul Rasool MH, et al. Effects of Breast Feeding and Nutritional Habits on Breast Cancer in Females. PAKISTAN JOURNAL OF MEDICAL & HEALTH SCIENCES. 2017;11(3):1078-81. doi:N/A
  19. Do MH, Lee SS, Jung PJ, Lee MH. Breast Feeding and Breast Cancer Risk: A Case-control Study in Korea. Nutritional Sciences. 2000;3(2):77-82. doi:N/A
  20. Lehman T, Shaik M, Modali R, Hrinczenko B. Effects of Breast-feeding and Oral Contraception on the Risk of Recurrence in Breast Cancer: A Multinational Study. doi:N/A
  21. Newcomb PA, Trentham-Dietz A. Breast feeding practices in relation to endometrial cancer risk, USA. Cancer Causes & Control. 2000;11:663-7. doi:10.1023/A:1008978624266
  22. Ing R, Ho JHC, Petrakis NicholasL. UNILATERAL BREAST-FEEDING AND BREAST CANCER. The Lancet. 1977;310(8029):124–7. doi:10.1016/S0140-6736(77)90131-3
  23. Jordan SJ, Cushing-Haugen KL, Wicklund KG, Doherty JA, Rossing MA. Breast-feeding and risk of epithelial ovarian cancer. Cancer Causes & Control. 2012;23:919-27. doi:10.1007/s10552-012-9963-4
  24. Titus-Ernstoff L, Rees JR, Terry KL, Cramer DW. Breast-feeding the last born child and risk of ovarian cancer. Cancer Causes & Control. 2010;21:201-7. doi:10.1007/s10552-009-9450-8
  25. Gwinn ML, Lee NC, Rhodes PH, Layde PM, Rubin GL. Pregnancy, breast feeding, and oral contraceptives and the risk of epithelial ovarian cancer. Journal of Clinical Epidemiology. 1990;43(6):559–68. doi:10.1016/0895-4356(90)90160-Q
  26. Alotiby AA. The role of breastfeeding as a protective factor against the development of the immune-mediated diseases: A systematic review. Frontiers in Pediatrics. 2023;11:1086999. doi:10.3389/fped.2023.1086999
  27. Murphy S, Carter L, Al Shizawi T, Queally M, Brennan S, O’Neill S. Exploring the relationship between breastfeeding and the incidence of infant illnesses in Ireland: evidence from a nationally representative prospective cohort study. BMC Public Health. 2023;23(1):140. doi:10.1186/s12889-023-15045-8
  28. Donovan SM. The role of lactoferrin in gastrointestinal and immune development and function: a preclinical perspective. The Journal of pediatrics. 2016;173:S16-28. doi:10.1016/j.jpeds.2016.02.072
  29. Cacho NT, Lawrence RM. Innate immunity and breast milk. Frontiers in immunology. 2017;8:584. doi:10.3389/fimmu.2017.00584
  30. Victora CG, Bahl R, Barros AJ, França GV, Horton S, Krasevec J, Murch S, Sankar MJ, Walker N, Rollins NC. Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect. The lancet. 2016;387(10017):475-90. doi:10.1016/S0140-6736(15)01024-7
  31. Labbok MH. Effects of breastfeeding on the mother. Pediatric Clinics of North America. 2001;48(1):143-58. doi:10.1016/S0031-3955(05)70290-X
  32. Krol KM, Grossmann T. Psychological effects of breastfeeding on children and mothers. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2018;61(8):977. doi:10.1007/s00103-018-2769-0
  33. Stordal B. Breastfeeding reduces the risk of breast cancer: A call for action in high‐income countries with low rates of breastfeeding. Cancer Medicine. 2023;12(4):4616-25. doi:10.1002/cam4.5288
  34. Gajalakshmi V, Mathew A, Brennan P, Rajan B, Kanimozhi VC, Mathews A, Mathew BS, Boffetta P. Breastfeeding and breast cancer risk in India: A multicenter case‐control study. International journal of cancer. 2009;125(3):662-5. doi:10.1002/ijc.24429
  35. Extended Breastfeeding Reduces the Risk of Ovarian Cancer [Internet]. OCRA. 2013. Available from: https://ocrahope.org/news/extended-breastfeeding-reduces-the-risk-of-ovarian-cancer/#:~:text=Women%20who%20had%20three%20children
  36. Russo J, Russo IH. Toward a physiological approach to breast cancer prevention. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 1994;3(4):353-64. doi:N/A
  37. Byers TI, Graham S, Rzepka T, Marshall J. Lactation and breast cancer: evidence for a negative association in premenopausal women. American Journal of Epidemiology. 1985;121(5):664-74. doi:10.1093/aje/121.5.664

Similar Articles

You may also start an advanced similarity search for this article.

Keywords
Copyright (c) 2024 Barw Medical Journal Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Send mail to Author

Send Cancel
Copyright© Barw Publications 2023. All rights reserved
Themes by Openjournaltheme.com